Tag Archives: ammonia-oxidizing bacteria (AOB)

WORLD MICROBIOME DAY 27 JUNE 2019

 

Source: MotherDirt.com
Today is World Microbiome Day, a day devoted to celebrating all things microbial worldwide. The theme of the 2019 World Microbiome Day is ANTIBIOTIC RESISTANCE.
The day is dedicated to introducing international microbiome researchers to the public to raise awareness of the diverse world of microbes and how they need to be protected.
“Microorganisms (e.g. bacteria, fungi, viruses, archaea, etc) can be found everywhere in and on plants, animals, water, soil, food and humans. Within each of those habitats, microorganisms live together in communities called microbiomes. Microbiomes have an effect on (amongst others) human health; therefore, scientists are exploring how these communities of organisms co-exist with each other, with us and our environment.
“The 2019 World Microbiome Day theme is ‘Antibiotic Resistance’. Antibiotics are life-saving drugs against harmful bacterial infections that also affect the beneficial bacteria of the human, animal and plant microbiome. Overuse and misuse of antibiotics can lead to bacteria becoming resistant to the antibiotics making them ineffective. That’s why we need everybody to help raise the profile of this important issue and empower people to use antibiotics responsibly.” (World Microbiome Day, 2019)

World Microbiome Day 2018: “Mind Our Microbes”

 

 

HUMAN & OTHER MICROBIOMES

The human body contains collections of micro-organisms that include bacteria, protozoa, fungi, viruses and other one-celled organisms living in and on the body. Our bodies’ interactions with these microbes are crucial to the state of our health. These microbes live both INSIDE us –   in our digestive organs and lungs — and externally ON us – on our skin, mouth, genitals. Our microbiomes serve many essential functions in the body:  aiding digestion, supporting the immune system living in our guts and preventing infections. In addition, the gut microbiome continually  interacts with the brain, making it possible to support mental health through changing your gut microbiome. Humans are actually ECOSYSTEMS made up of our human cells and billions of these other micro-organisms. (World Microbiome Day, 2019)
Other animals on earth living on the land, in the water and the sky also need ecosystems made up of their own cells and a healthy variety of micro-organisms. The  same is true of plants’, the soils’, food sources’, oceans’, rivers’ and lakes’ ecosystems.
The poisoning of the ecosystems on our planet and climate change have done serious damage to the planet – with dire consequences.
Source: xascaleproject.org
I’ll let Jasmina Agranovic, whose principal interest is the skin microbiome (she’s the president of Mother Dirt*), speak in her own words to explain the importance of the various microbiomes in the human body:
“There’s an important dynamic at play between consumers and scientists right now. These two worlds were once far apart, but have recently started to overlap. This is especially evident in the field of the microbiome, where it could even be argued that public demand has become a driver of the science. Never before has a topic been spoken about so publicly and marketed ahead of extensive clinical and scientific validation.
“The gut microbiome has done a lot of the heavy lifting in reframing our relationship with bacteria. As people are becoming more aware of the benefits of good bacteria in digestive health, there is also a shifting view our bodies as ecosystems, rather than simply tissues and organs. While still a stretch, it is slowly becoming less of one to see how the same is true for their skin….
Source: Wellness Mama
“The impact of this ongoing and prevalent conversation is something you can see already: It’s now becoming more common for primary care doctors to prescribe a probiotic in conjunction with antibiotics. Kombucha has transformed from a specialty item found only at health food stores to something you can pick up at your local drug store. Kimchi and Sauerkraut have become dietary staples, along endless other fermented and probiotic-infused foods.
“This public interest has placed more scrutiny on the science. Together, these are driving a big financial appetite by investors, creating support for entrepreneurs and researchers with big ideas in the space.
“Companies like Ubiome specialize in at-home gut and vaginal biome screenings. OpenBiome works in stool donations, enabling people to get live-saving fecal transplants. Seres Therapeutics was also the first publicly traded microbiome biotech company based off of their work on treatments for C Diff. In 2016 the FDA banned triclosan, which is the active ingredient in many antibacterial soaps, stating it’s no more effective than washing with soap and water, and that it could actually do more harm than good over time.
“Even museums have started to showcase the microbiome as part of our future. The Victoria & Albert Museum in London has an exhibit on display until Nov 2018 called “The Future Starts Here: 100 projects shaping the world of tomorrow” where one of the projects included in the show is Mother Dirt representing the skin biome and what might exist in a future home.
“So what’s the next big thing in bacteria? We earnestly believe that relationship with the microbial world is one of the most important shifts in public health of our generation. For many, the microbiome and the importance of good bacteria in and on your body might be the missing piece of the puzzle when it comes to many of the health issues we are still trying to solve. We don’t know what we don’t know, but many are rightfully excited at the prospect of exploring this field for all the potential it seems to hold. The public interest has helped push the gas pedal on the scientific progress. As we continue to make progress in new discoveries in the field, it will be increasingly important that the science remains rigorous and that we also temper expectations.
“Keep asking questions, keep challenging the norm, and keep pushing for more, and together we’ll create a world where clean comes with healthy.”

 

*MOTHER DIRT

Mother Dirt is a company in Cambridge MA that makes skin biome-friendly products based on extensive research on the skin microbiome and the Ammonia-Oxidizing Bacteria (AOB) our skin needs to stay healthy .
Source: MotherDirt.com

We believe that the diverse world of microbiomes deserves more recognition due to its effect on human, animal and environmental health! Join us in celebrating World Microbiome Day 2019 and communicating the effects of antibiotics on the microbiome.

(World Microbiome Day 6/27/2019)
You can go to the World Microbiome Day 6/27/2019 site to learn more about the importance of microbiomes and take some quizzes to test your knowledge about six microbiomes: Food, Plant, Soil, Animal, Marine and Human.

 

ADDITIONAL READING

What’s in the Human Microbiome

How the Gut Microbiome Influences the Brain – and Vice Versa

Repair the Soil’s Microbiome to Resolve the Climate Crisis

Antibiotics, the Gut Microbiome & the Rest of the Body

AO Biome: Clean vs Sterile

Follow Up on AO+ Living Bacterial Skin Tonic

There are additional posts on AllergiesAndYourGut about the gut and other microbiomes. You can search on the site for what interests you.

 

REFERENCES

Hardin, J.R. (12/18/2014). AO Biome: Clean vs Sterile.  https://allergiesandyourgut.com/2014/12/18/ao-biome-clean-vs-sterile/

Hardin, J.R. (4/9/2015). How the Gut Microbiome Influences the Brain – and Vice Versa. See: https://allergiesandyourgut.com/2015/04/09/how-the-gut-microbiome-influences-the-brain-and-vice-versa/

Hardin, J.R. (6/13/2015). What’s in the Human Microbiome. See: https://allergiesandyourgut.com/2015/06/13/whats-in-the-human-microbiome/

Hardin, J.R. (1/29/2016). Repair the Soil’s Microbiome to Resolve the Climate Crisis. See: https://allergiesandyourgut.com/2016/01/29/4404/

Hardin, J.R. (2/25/2016).  Follow Up on AO+ Living Bacterial Skin Tonic. See: https://allergiesandyourgut.com/2014/09/27/follow-ao-living-bacterial-skin-tonic/

© Copyright 2019. Joan Rothchild Hardin. All Rights Reserved.

DISCLAIMER:  Nothing on this site or blog is intended to provide medical advice, diagnosis or treatment.

 

 

Follow Up on AO+ Living Bacterial Skin Tonic

Updated 2/25/2016.

 

images-1
I first wrote about AOBiome’s brilliant new approach to skin health and cleanliness in Living Bacterial Skin Tonic – Instead of Soap?! (June 7, 2014).
AO+ Refreshing Cosmetic Mist is a liquid developed by a biotech start up company in Cambridge MA to spray on our bodies in lieu of – or as an adjunct to – taking showers. Showering with most soaps and shampoos kills all the healthy elements of our skin’s microbiome. AOBiome’s new living bacterial skin tonic, made of safe live-cultured Nitrosomonas bacteria, replenishes the biome of microscopic organisms that should live on our skin.
(Source: AOBiome)
(Source: AOBiome)

 

From the AO Biome website:

THE SCIENCE

Skin has a Broad Systemic Impact

A healthy microbiome is necessary for skin to do its work optimally. The human skin microbiome requires Ammonia Oxidizing Bacteria (AOB) to function well.

AOBs Are Everywhere in Nature

In the wild, humans had this on their skin – a mutually beneficial working relationship! AOB in the natural environment regulate our nitrogen metabolism. Unfortunately, AOB on our bodies have been impaired by culture and behavior.

Why Does This Matter?

Modern hygiene has selectively depleted the natural balance of the skin microbiome particularly affecting AOB. By restoring the appropriate AOB levels, we believe a range of human health conditions could be impacted. AOBiome is interested in exploring potential physiologic effects including:

Improving skin architecture
Improving skin architecture
Preventing infection
Preventing infection
Improving vascularization
Improving vascularization

 

 

 

 

 

AOBs: What I'm spraying on my skin daily to improve my skin microbiome
AOBs: What I’m spraying on my skin daily to improve my skin microbiome

 

 

MY EXPERIENCE WITH AO+ SPRAY

After waiting a few months for the company to catch up to demand for their new bacterial spray, my first month’s supply arrived in early September 2014: Four spray bottles nestled inside an elegant box  – one bottle for each week – with clear use instructions. Each bottle contains over 100 sprays to least a week at about 15 sprays/day. The bacteria in the spray will survive about a month at room temperature so the bottle I’m using sits on the bathroom counter. The other bottles are stored in the fridge, where they’ll last for at least six months.

 

 

 

AO+ Refresjomg Cosmetic Mist - live cultured ammonia-oxidizing bacteria (AOB). (Source: www.microbesandme.com)
AO+ Refresjomg Cosmetic Mist – live cultured ammonia-oxidizing bacteria (AOB). (Source: www.microbesandme.com)
I began using the spray on September 7th immediately after toweling off from a shower – only on my arms, neck and chest at first – instead of my usual Jurlique Lavender Body Care Lotion. I showered using Dr. Bronner’s Lavender Soap (bar version) on my feet, crotch, arm pits and lightly on my face. As I was doing before, I’ve continued using Jurlique’s Skin Balancing Face Oil on my face and Erbe’s Orange C Serum around my eyes where the skin is delicate and usually dry.
I’ve also continued washing my hair with Jurlique’s Lavender Conditioner about once weekly. (I’ve got fine, curly hair so shampoo isn’t good for it – too drying. Conditioner does a fine job of cleaning out the dirt and excess oils.)
BTW, all the products mentioned above contain only high quality ingredients and no parabens, estrogen disrupters, carcinogens or other harsh, dangerous chemicals.
I stopped using antiperspirants many years ago once I understood that the body needs to perspire but, not quite ready to retire my deodorant, I’ve continued using my favorite: Tom’s Long Lasting Deodorant (Unscented).
What I noticed right away after that first application was that the skin where I’d applied the AO+ Refreshing Cosmetic Mist smelled like a baby’s skin – a ‘this makes me smile and feel good all over’ scent, not the shitty diaper smell. And after just one application, my skin felt and looked soft, smooth and well-nourished.

 

 

images

After a few days, I started using the bacterial spray on my legs and the tops of my feet too. This skin is usually pretty dry but has become nicely hydrated with the spray.
I tried the spray on my face but didn’t like the tight feeling it produced so returned to using face oil. Interestingly, I’ve never felt it at all on the rest of my body. This seemed to be unique to my face. Perhaps I’ll give it another try on my face.
That first bottle, with the daily use described above, lasted for 20 days – so clearly I wasn’t using 15 sprays/day.
Yesterday, with the second bottle, I started using the spray on my entire body – with the exception of my face, armpits, the parts of my back I can’t reach, and soles of my feet. That probably amounted to 12-15 sprays.
I’m thinking I’ll start using it on my hair too starting tomorrow.
One of the more interesting things that started happening after two weeks of using the spray on my arms is that some patches of seborrheic keratosis began to dry up. I expect they’ll eventually fall off! This is most welcome.

 

An example of a seborrheic keratosis. (Source: www.medicinenet.com)
An example of a seborrheic keratosis. (Source: www.medicinenet.com)

 

Seborrheic keratosis is a benign skin disorder characterized by rough, raised areas resulting from excessive growth of the top layer of skin cells. Mine are a light brown but they can range from light tan to black. They’re odd looking – like they’re just sitting on top of my skin. They’re sometimes referred to as “barnacles of old age.” How delightful. I’ll be glad to see them go.

 

BACTERIA ARE YOUR FRIENDS

(Source: www.microbesandme.com)
(Source: www.microbesandme.com)
The bottom line is that I’m quite happy to be an early user of AO Biome’s AO+ Refreshing Cosmetic Mist and greatly look forward to its being widely available. My hope is that the existence of this product will help educate people to differentiate between USEFUL bacteria and HARMFUL ones instead of viewing all bacteria as dangerous and in need of being destroyed.
I quote Michael Pollan from his wonderful article Some of My Best Friends Are Germs (Pollan, 2013):

As a civilization, we’ve just spent the better part of a century doing our unwitting best to wreck the human-associated microbiota.

 

 

There's a difference between good bacteria and bad bacteria. Nurture your good bacteria instead of trying to kill them off. (Source: naturallyimmune.org)
There’s a difference between good bacteria and bad bacteria. Nurture your good bacteria instead of trying to kill them off. (Source: naturallyimmune.org)

 

I highly recommend perusing AOBiome’s website, facebook and FAQ for more fascinating information on the needs of the skin microbiome and the science behind their product.

 

 

imgres

 

 

 

 

 

GUT/BRAIN/SKIN AXIS (Bowe & Logan, 2011) (Kresser, 2014)

 

I’ve been writing mostly on the gut microbiome on this site. Here’s information on how the skin flora microbiome fits in:

 

 

The trillions of microbes in and on our bodies are key to understanding our health. (Source: organicfitness.com)
The trillions of microbes in and on our bodies are key to understanding our health. (Source: organicfitness.com)

 

70 years ago, dermatologists John H. Stokes and Donald M. Pillsbury proposed a gastrointestinal mechanism for the observed overlap between depression, anxiety and skin conditions, such as acne.
They  hypothesized that emotional states might alter intestinal microflora, increase intestinal permeability and contribute to systemic inflammation. Among the acne remedies they suggested were Lactobacillus acidophilus cultures. Imbalances in the gut microbiota and oral probiotics produce systemic inflammation and oxidative stress, upset glycemic control and tissue lipid content, influence mood  and cause skin conditions such as acne.

 

EVIDENCE OF A  CONNECTION BETWEEN GUT PROBLEMS AND SKIN DISORDERS

 

  • People with acne are also at higher risk for suffering from GI distress, such as constipation, halitosis and gastric reflux.
  • A recent study found that teens with acne and other seborrheic conditions were 37% more likely to have abdominal bloating.
  • People with acne rosacea have been found to be 10 times more likely than healthy controls to have small intestine bacterial overgrowth (SIBO), a condition involving inappropriate growth of bacteria in the small intestine. Correcting their SIBO markedly improved their acne rosacea.
  • 14% of patients with ulcerative colitis and 24% of patients with Crohn’s disease also have skin disorders.
  • Celiac disease sufferers are also apt to have cutaneous manifestations, such as dermatitis herpetiformis (occurs in 1/4 of people with celiac). Celiacs also have increased frequency of oral mucosal lesions, alopecia and vitiligo.
  • A recent study showed that a drug used to treat psoriasis is also effective for Crohn’s.
  • In another study, 56 patients with acne who consumed a Lactobacillus fermented dairy beverage for 12 weeks saw clinical improvement.
  • Pasteurized, unfermented dairy is associated with acne but fermented dairy is not.

 

Scientists are now validating the existence of a gut-brain-skin axis – and recommending oral probiotics to cure and prevent acne and other skin conditions.
Noted practitioner of functional and integrative medicine,  licensed acupuncturist, and health blogger Chris Kresser puts it simply:
                              If you want to heal your skin, you have to heal your gut.
And, as I’ve noted throughout this site, improving your gut flora will reduce chronic inflammation everywhere in the body and keep you from developing allergies, one or more of the many autoimmune conditions and possibly even cancers – or let your body heal if you already have one of these conditions – and also improve your mood.

 

 

 

(Source: www.drchadmorton.com)
Your skin is a direct reflection of your digestive tract. (Source: www.drchadmorton.com)

 

2/25/2016:
In another brilliant move, AO Biome has renamed its skin-microbiome friendly spray mist, shampoo, and cleanser MOTHER DIRT.

 

 

Source: www.persiankittykat.com)
Source: www.persiankittykat.com)

 

 

 

REFERENCES

AOBiome. (2013-2014). facebook.  See:  https://www.facebook.com/AOBiome

AOBiome. (2014). FAQ. See: https://www.aobiome.com/faq

AOBiome. (2014). Pioneering bacterial therapy for the skin. See: https://www.aobiome.com/company

Bowe, W.P. & Logan, A.C.  (2011). Acne vulgaris, probiotics and the gut-brain-skin axis – back to the future? Gut Pathogens, 3: 1. See: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038963/

Hardin, J.R. (2014). Living Bacterial Skin Tonic – Instead of Soap?! Allergies And Your Gut. See:  http://allergiesandyourgut.com/2014/06/07/living-bacterial-skin-tonic-instead-bathing/

Kresser, C. (2014). The gut-skin connection: how altered gut function affects the skin. See:  http://chriskresser.com/the-gut-skin-connection-how-altered-gut-function-affects-the-skin

Polan, M. (2013). Some of My Best Friends Are Germs. New York Times Magazine, May 15 2013. See:  http://www.nytimes.com/2013/05/19/magazine/say-hello-to-the-100-trillion-bacteria-that-make-up-your-microbiome.html?pagewanted=all&_r=0


© Copyright 2014 Joan Rothchild Hardin. All Rights Reserved.

 

DISCLAIMER:  Nothing on this site or blog is intended to provide medical advice, diagnosis or treatment.